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人肝細胞 HH

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產品名稱: 人肝細胞 HH
產品型號: HH
產品展商: ScienCell
產品價格: 0.00 元
產品文檔: 無相關文檔

簡單介紹

人肝細胞 HH 人肝細胞 HH 上海 安徽 合肥 ScienCell細胞庫?


人肝細胞 HH  的詳細介紹
肝臟是許多重要功能的關鍵器官，包括能量代謝、外源性化學物質生物轉化、生理和病理條件下血漿蛋白合成、以及解毒作用[1]。人肝細胞是多功能細胞，包括蛋白質合成、膽固醇合成、儲存蛋白質、產生并分泌膽汁以及解毒作用[1-3]。HH是體外培養用來研究肝功能、新陳代謝和肝病非常好的模型。了解肝臟的分子機制可能有助于闡明治療肝臟疾病的新療法。
Sciencell研究實驗室的臍靜脈內皮細胞是從人肝臟分離得到的，原代凍存，冰凍運輸。每管細胞密度超過5×10^6/ml。細胞特性經白蛋白、cytokeratin-18 and vimentin免疫熒光鑒定。本細胞經檢測不含HIV-1、HBV、HCV、支原體、細菌、酵母菌和真菌。HH不能擴大培養或者產期培養，因為它不能增殖。

推薦培養基：肝細胞培養基 (HM, Cat. #5201)
貨號 5200
產地 美國
縮寫 HH
規格 1 x 10^6 /1ml
用途 科研
儲存 液氮
運輸 干冰
關鍵字 人肝細胞 HH  人肝細胞 HH  人肝細胞 HH  人肝細胞 HH  人肝細胞 HH  人肝細胞 HH  人肝細胞 HH  人肝細胞 HH  
公司簡介                         
     合肥星肽生物科技有限公司作為專業的ScienCell中國代理商，專業經營實驗室科研用原代細胞、原代細胞專用培養基、原代細胞無血清培養基、干細胞、干細胞培養基、干細胞無血清培養基的研究和開發。合肥星肽生物科技有限公司始終致力于為客戶提供可靠的研究材料以及方便快捷的服務，對購買項目的前期資料提供,中期合同保證,后期貨物跟蹤到 *終售后的確保項目準確到位，都有相關專業人士進行維護,確保您在合肥合肥星肽生物科技有限公司公司獲得*上等服務！
聯系方式

               何經理，合肥星肽生物科技有限公司，Tel：0551-63802898      400-8702-898，                                  

               E-mail：info@qingbio.com      http://www.42vq.com      QQ:514713116

1.) Chiang TS, Yang KC, Chiou LL, Huang GT, Lee HS.(2014) "Enhancement of CYP3A4 Activity in Hep G2 Cells by Lentiviral Transfection of Hepatocyte Nuclear Factor-1 Alpha." PloS one. 9: e94885.

2.) Liu Y, Liu A, Xu Z, Yu W, Wang H, Li C, Lin J. (2011) "XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells." Apoptosis. 16: 502-10.

3.) Braconi C, Valeri N, Gasparini P, Huang N, Taccioli C, Nuovo G, Suzuki T, Croce CM, Patel T. (2010) "Hepatitis C virus proteins modulate microRNA expression and chemosensitivity in malignant hepatocytes." Clin Cancer Res. 16: 957-66.

4.) Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N. (2010) "The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib." Hepatology. 52: 1310-21.

5.) Liu Y, Li PK, Li C, Lin J. (2010) "Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells." J Biol Chem. 285: 27429-39.

6.) Shen Q, Cicinnati VR, Zhang X, Iacob S, Weber F, Sotiropoulos GC, Radtke A, Lu M, Paul A, Gerken G, Beckebaum S. (2010) "Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion." Mol Cancer. 9: 227.

7.) Shimizu S, Takehara T, Hikita H, Kodama T, Miyagi T, Hosui A, Tatsumi T, Ishida H, Noda T, Nagano H, Doki Y, Mori M, Hayashi N. (2010) "The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma." J Hepatol. 52: 698-704.

8.) Yeon JH, Na D, Park JK. (2010) "Hepatotoxicity assay using human hepatocytes trapped in microholes of a microfluidic device." Electrophoresis. 31: 3167-74.

9.) Braconi C, Meng F, Swenson E, Khrapenko L, Huang N, Patel T. (2009) "Candidate therapeutic agents for hepatocellular cancer can be identified from phenotype-associated gene expression signatures." Cancer. 115: 3738-48.

10.) Huang Y, Song N, Ding Y, Yuan S, Li X, Cai H, Shi H, Luo Y. (2009) "Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis." Cancer Res. 69: 7529-37.

11.) Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. (2007) "MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer." Gastroenterology. 133: 647-58.

12.) Nahmias Y, CAS:ali M, Barbe L, Berthiaume F, Yarmush ML. (2006) "Liver endothelial cells promote LDL-R expression and the uptake of HCV-like particles in primary rat and human hepatocytes." Hepatology. 43: 257-65.

Question:

Dear Customer Service, I am Zhonghui Zhang who is working in Dr. Wen-Shu Wu’s lab at the University of Illinois at Chicago (UIC). We previously ordered your HH cells and HH medium 09/29/2008 in Maine Medical Center Research Institute (Our lab moved from MMCRI to UIC in 2013). We would like to order a new HH cells from your company, but we don’t want to order this cell from the same donor. Would you please tell me whether the cells were from different donors? By the way, would you please give us some information about previous HH cells (such as age, gender, race and etc.)? Thank you so much! Zhonghui Zhang, Ph.D Section of Hematology/Oncology, Department of Medicine University of Illinois at Chicago 909 S Wolcott Ave, Room 5140 Chicago, IL 60612 Phone: 312-996-2324 (office) or 207-420-5603 (cell)

Answers:

  • Posted by Manoj Sharma on Thursday, January 7, 2016

    hello,

    We need lot number to check donor information. And yes we have other lots from different donors. thanks for your interest

    SCIENCELL TEAM

    Question:

    Can you provide more detail on the source of these cells and general characteristics other than "HH from ScienCell Research Laboratories are isolated from human liver"? Derived from healthy liver tissue, any particular liver site for selection of cellular material, how derived, normal karyotype?

    Answers:


    Posted by Karishma Shah on Thursday, August 27, 2015

    Hi Jeff,

    Thanks for asking! Human Hepatocytes are isolated from healthy liver tissue. We have donor information for each lot, if you would like specific information please email sales@sciencellonline.com or call us at 760-602-8549. Due to tissue limitation, there is no particular site in the liver we get cells from. We use the entire liver tissues we obtain. Please let us know if you have any more questions. Thank you!

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